Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP091061	ABCB11	ABCB11	Homo sapiens (human)	[ethinyl estradiol co-treated with cholic acids] affects the expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Homo sapiens (human)	Ethinyl estradiol results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Homo sapiens (human)	Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|prkaca protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [chenodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]\|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]\|ethinyl estradiol results in decreased expression of ABCB11 mrna\|chenodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|8-bromo cyclic adenosine monophosphate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|prkacb protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	Alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]\|pregna-4,17-diene-3,16-dione promotes the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	ESR1 gene mutant form inhibits the reaction [ethinyl estradiol results in increased expression of ABCB11 mrna]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	ESR1 protein promotes the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	Ethinyl estradiol affects the expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	Ethinyl estradiol results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	Ethinyl estradiol results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	Ethinyl estradiol results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	[metformin co-treated with ethinyl estradiol] results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	SRT1720 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|srt1720 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Mus musculus (house mouse)	[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	NR1H4 protein inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]\|prkaa1 protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]\|gw 4064 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Ethinyl estradiol results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Ethinyl estradiol results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP091061	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082519	ABCB11	ABCB11	Homo sapiens (human)	Morin inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]\|morin results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082880	ABCB11	ABCB11	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:42
BIMP082232	ABCB11	ABCB11	Mus musculus (house mouse)	[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082233	ABCB11	ABCB11	Homo sapiens (human)	Clavulanic acid results in decreased expression of ABCB11 mrna\|clavulanic acid inhibits the reaction [GW 4064 results in increased expression of ABCB11 mrna]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082566	ABCB11	ABCB11	Homo sapiens (human)	Lasiocarpine results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082619	ABCB11	ABCB11	Mus musculus (house mouse)	[tectorigenin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCB11 protein\|[tectorigenin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082571	ABCB11	ABCB11	Homo sapiens (human)	Senkirkine results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP082316	ABCB11	ABCB11	Homo sapiens (human)	Isobavachalcone inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]\|enzymes and coenzymes inhibits the reaction [isobavachalcone inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]]	https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Homo sapiens (human)

[ethinyl estradiol co-treated with cholic acids] affects the expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Homo sapiens (human)

Ethinyl estradiol results in decreased activity of ABCB11 protein

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Homo sapiens (human)

Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|prkaca protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [chenodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]|ethinyl estradiol results in decreased expression of ABCB11 mrna|chenodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|8-bromo cyclic adenosine monophosphate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|prkacb protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

Alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]|pregna-4,17-diene-3,16-dione promotes the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

ESR1 gene mutant form inhibits the reaction [ethinyl estradiol results in increased expression of ABCB11 mrna]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

ESR1 protein promotes the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

Ethinyl estradiol affects the expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

Ethinyl estradiol results in decreased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

Ethinyl estradiol results in decreased expression of ABCB11 protein

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

Ethinyl estradiol results in increased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

[metformin co-treated with ethinyl estradiol] results in decreased expression of ABCB11 protein

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

SRT1720 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|srt1720 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Mus musculus (house mouse)

[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in increased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Rattus norvegicus (Norway rat)

NR1H4 protein inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]|prkaa1 protein affects the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|dorsomorphin inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|gw 4064 inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Rattus norvegicus (Norway rat)

Ethinyl estradiol results in decreased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Rattus norvegicus (Norway rat)

Ethinyl estradiol results in decreased expression of ABCB11 protein

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP091061

ABCB11

Rattus norvegicus (Norway rat)

Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082519

ABCB11

Homo sapiens (human)

Morin inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|morin results in decreased activity of ABCB11 protein

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082880

ABCB11

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:42

BIMP082232

ABCB11

Mus musculus (house mouse)

[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082233

ABCB11

Homo sapiens (human)

Clavulanic acid results in decreased expression of ABCB11 mrna|clavulanic acid inhibits the reaction [GW 4064 results in increased expression of ABCB11 mrna]

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082566

ABCB11

Homo sapiens (human)

Lasiocarpine results in decreased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082619

ABCB11

Mus musculus (house mouse)

[tectorigenin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCB11 protein|[tectorigenin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082571

ABCB11

Homo sapiens (human)

Senkirkine results in decreased expression of ABCB11 mRNA

https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP082316

ABCB11

Homo sapiens (human)

Isobavachalcone inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]|enzymes and coenzymes inhibits the reaction [isobavachalcone inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]]

https://ctdbase.org/detail.go?type=gene&acc=8647