Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP073152	ABCB11	ABCB11	Homo sapiens (human)	Indomethacin results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073107	ABCB11	ABCB11	Mus musculus (house mouse)	[dexamethasone co-treated with ibuprofen] results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073663	ABCB11	ABCB11	Homo sapiens (human)	Vitamin K 3 results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP075130	ABCB11	ABCB11	Homo sapiens (human)	ABCB11 protein results in increased transport of notoginsenoside R1	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP075559	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Ochratoxin A results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP075124	ABCB11	ABCB11	Homo sapiens (human)	ABCB11 protein results in increased transport of ginsenoside re	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073725	ABCB11	ABCB11	Homo sapiens (human)	Nicardipine inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073725	ABCB11	ABCB11	Homo sapiens (human)	Nicardipine results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073729	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Methoxsalen results in decreased expression of ABCB11 mrna\|methoxsalen results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073199	ABCB11	ABCB11	Homo sapiens (human)	Irbesartan results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073239	ABCB11	ABCB11	Homo sapiens (human)	[isoniazid co-treated with rifampin co-treated with pyrazinamide co-treated with ethambutol] affects the expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073239	ABCB11	ABCB11	Mus musculus (house mouse)	Isoniazid results in decreased expression of ABCB11 protein\|[rifampin co-treated with isoniazid] results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073239	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	Obeticholic acid inhibits the reaction [isoniazid results in decreased expression of ABCB11 mrna]\|isoniazid results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073239	ABCB11	ABCB11	Rattus norvegicus (Norway rat)	[lipopolysaccharides co-treated with isoniazid] results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073529	ABCB11	ABCB11	Homo sapiens (human)	Loratadine inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073529	ABCB11	ABCB11	Homo sapiens (human)	Loratadine results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP073396	ABCB11	ABCB11	Homo sapiens (human)	Kynurenic acid inhibits the reaction [ABCB11 protein results in increased uptake of taurocholic acid]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071851	ABCB11	ABCB11	Mus musculus (house mouse)	[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071212	ABCB11	ABCB11	Homo sapiens (human)	Ciglitazone results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071247	ABCB11	ABCB11	Mus musculus (house mouse)	Ciprofibrate results in decreased expression of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071726	ABCB11	ABCB11	Homo sapiens (human)	Diclofenac inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071726	ABCB11	ABCB11	Homo sapiens (human)	Diclofenac results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071304	ABCB11	ABCB11	Homo sapiens (human)	Clotrimazole results in decreased activity of ABCB11 protein\|clotrimazole inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071289	ABCB11	ABCB11	Homo sapiens (human)	Clofibrate results in decreased activity of ABCB11 protein	https://ctdbase.org/detail.go?type=gene&acc=8647
BIMP071289	ABCB11	ABCB11	Mus musculus (house mouse)	Clofibrate results in increased expression of ABCB11 mRNA	https://ctdbase.org/detail.go?type=gene&acc=8647

BIMP073152

ABCB11

Homo sapiens (human)

Indomethacin results in decreased activity of ABCB11 protein