SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB11
|
Rattus
|
ABCB11 protein affects the transport of ursodeoxycholic acid
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]]|ursodeoxycholic acid results in increased expression of ABCB11 mrna|ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 mrna]|ursodeoxycholic acid results in increased expression of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Ursodeoxycholic acid inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCB11 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Ursodeoxycholic acid inhibits the reaction [1-naphthylisothiocyanate results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Ursodeoxycholic acid inhibits the reaction [ethinyl estradiol results in decreased expression of ABCB11 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Chelerythrine inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]|chelerythrine results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased methylation of ABCB11 promoter|benzo(a)pyrene results in increased methylation of ABCB11 5' UTR
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased mutagenesis of ABCB11 gene
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Aconitine inhibits the reaction [ABCB11 protein results in increased transport of taurodeoxycholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Zidovudine results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Glyburide inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Glyburide results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
[glyburide results in decreased activity of ABCB11 protein] which results in decreased export of taurodeoxycholic acid
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
[bile acids and salts co-treated with glyburide] results in decreased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Mus musculus (house mouse)
|
Glyburide results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Glyburide results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
[glyburide results in decreased activity of ABCB11 protein] which results in decreased secretion of rosuvastatin calcium
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Rattus norvegicus (Norway rat)
|
Glyburide results in increased expression of ABCB11 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:42
|
||
|
ABCB11
|
Homo sapiens (human)
|
Glimepiride inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Glimepiride results in decreased activity of ABCB11 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
||
|
ABCB11
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [ABCB11 protein results in increased transport of taurocholic acid]
|
https://ctdbase.org/detail.go?type=gene&acc=8647
|
No matching records found on this page.