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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA8
|
Homo sapiens (human)
|
ABCA8 protein affects the transport of estrone sulfate
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Digoxin inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Rattus norvegicus (Norway rat)
|
Clofibrate results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Indomethacin results in increased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Doxorubicin results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Ochratoxin A inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]|abca8 protein affects the transport of ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Xenopus tropicalis (tropical clawed frog)
|
Ethinyl estradiol results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Triclosan results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Adenosine triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
ABCA8 protein affects the transport of leukotriene C4
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
[estradiol co-treated with TGFB1 protein] results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Estradiol results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
[progesterone co-treated with estradiol] results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Rattus norvegicus (Norway rat)
|
Oxycodone results in increased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Rattus norvegicus (Norway rat)
|
Sulfadimethoxine results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which affects the expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Cyclosporine results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Cyclosporine results in decreased methylation of ABCA8 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Gallus gallus (chicken)
|
T-2 toxin results in increased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Licochalcone B results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
ABCA8 protein affects the transport of p-aminohippuric acid
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Aflatoxin B1 affects the expression of ABCA8 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
||
|
ABCA8
|
Homo sapiens (human)
|
Aflatoxin B1 results in decreased methylation of ABCA8 gene|aflatoxin B1 results in decreased expression of ABCA8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10351
|
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