Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP070286	ACE	ACE	Rattus norvegicus (Norway rat)	Caffeine results in decreased methylation of ACE promoter\|caffeine results in increased expression of ACE protein\|caffeine results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP072198	ACE	ACE	Homo sapiens (human)	Valproic acid results in increased methylation of ACE gene	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073549	ACE	ACE	Rattus norvegicus (Norway rat)	Naringin inhibits the reaction [bisphenol A promotes the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]]\|bisphenol A promotes the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]\|naringin inhibits the reaction [NG-nitroarginine methyl ester promotes the reaction [bisphenol A results in increased activity of ACE protein]]\|ng-nitroarginine methyl ester promotes the reaction [bisphenol A results in increased activity of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073549	ACE	ACE	Rattus norvegicus (Norway rat)	Naringin inhibits the reaction [[NG-nitroarginine methyl ester co-treated with bisphenol A] results in increased activity of ACE protein]\|[ng-nitroarginine methyl ester co-treated with bisphenol A] results in increased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073549	ACE	ACE	Rattus norvegicus (Norway rat)	NG-nitroarginine methyl ester results in increased activity of ACE protein\|naringin inhibits the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073586	ACE	ACE	Sus scrofa (pig)	Deoxynivalenol results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073775	ACE	ACE	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:2707
BIMP073775	ACE	ACE	Homo sapiens (human)	ACE gene polymorphism affects the susceptibility to metoprolol	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073251	ACE	ACE	Rattus norvegicus (Norway rat)	Isoproterenol results in increased activity of ACE protein\|oleuropein inhibits the reaction [isoproterenol results in increased activity of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:2707
BIMP074608	ACE	ACE	Bos taurus (cattle)	Captopril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Homo sapiens (human)	Captopril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Mus musculus (house mouse)	Captopril inhibits the reaction [silicon dioxide results in increased expression of ACE protein]\|captopril inhibits the reaction [silicon dioxide results in increased expression of ACE mrna]\|captopril inhibits the reaction [AGT protein results in increased expression of ACE protein]\|captopril inhibits the reaction [AGT protein results in increased expression of ACE mrna]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Rattus norvegicus (Norway rat)	Captopril inhibits the reaction [pregabalin results in increased expression of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Homo sapiens (human)	Captopril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP074608	ACE	ACE	Homo sapiens (human)	Inhibitor	https://www.dgidb.org/genes/hgnc:2707
BIMP075245	ACE	ACE	Homo sapiens (human)	Stevioside results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP073152	ACE	ACE	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:2707
BIMP071587	ACE	ACE	Homo sapiens (human)	Dieckol results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP071152	ACE	ACE	Rattus norvegicus (Norway rat)	APLN protein modified form inhibits the reaction [fructose results in increased expression of ACE mrna]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP071152	ACE	ACE	Rattus norvegicus (Norway rat)	[bisphenol A co-treated with fructose] results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP071152	ACE	ACE	Rattus norvegicus (Norway rat)	Fructose results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP072300	ACE	ACE	Rattus norvegicus (Norway rat)	Doxorubicin affects the activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP072300	ACE	ACE	Rattus norvegicus (Norway rat)	Ramipril inhibits the reaction [doxorubicin results in increased expression of ACE mrna]\|doxorubicin results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP077135	ACE	ACE	Rattus norvegicus (Norway rat)	Resveratrol results in decreased expression of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP070286

ACE

Rattus norvegicus (Norway rat)

Caffeine results in decreased methylation of ACE promoter|caffeine results in increased expression of ACE protein|caffeine results in increased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP072198

ACE

Homo sapiens (human)

Valproic acid results in increased methylation of ACE gene

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073549

ACE

Rattus norvegicus (Norway rat)

Naringin inhibits the reaction [bisphenol A promotes the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]]|bisphenol A promotes the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]|naringin inhibits the reaction [NG-nitroarginine methyl ester promotes the reaction [bisphenol A results in increased activity of ACE protein]]|ng-nitroarginine methyl ester promotes the reaction [bisphenol A results in increased activity of ACE protein]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073549

ACE

Rattus norvegicus (Norway rat)

Naringin inhibits the reaction [[NG-nitroarginine methyl ester co-treated with bisphenol A] results in increased activity of ACE protein]|[ng-nitroarginine methyl ester co-treated with bisphenol A] results in increased activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073549

ACE

Rattus norvegicus (Norway rat)

NG-nitroarginine methyl ester results in increased activity of ACE protein|naringin inhibits the reaction [NG-nitroarginine methyl ester results in increased activity of ACE protein]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073586

ACE

Sus scrofa (pig)

Deoxynivalenol results in decreased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073775

ACE

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:2707

BIMP073775

ACE

Homo sapiens (human)

ACE gene polymorphism affects the susceptibility to metoprolol

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073251

ACE

Rattus norvegicus (Norway rat)

Isoproterenol results in increased activity of ACE protein|oleuropein inhibits the reaction [isoproterenol results in increased activity of ACE protein]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:2707

BIMP074608

ACE

Bos taurus (cattle)

Captopril results in decreased activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Homo sapiens (human)

Captopril results in decreased activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Mus musculus (house mouse)

Captopril inhibits the reaction [silicon dioxide results in increased expression of ACE protein]|captopril inhibits the reaction [silicon dioxide results in increased expression of ACE mrna]|captopril inhibits the reaction [AGT protein results in increased expression of ACE protein]|captopril inhibits the reaction [AGT protein results in increased expression of ACE mrna]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Rattus norvegicus (Norway rat)

Captopril inhibits the reaction [pregabalin results in increased expression of ACE protein]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Homo sapiens (human)

Captopril results in decreased activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP074608

ACE

Homo sapiens (human)

Inhibitor

https://www.dgidb.org/genes/hgnc:2707

BIMP075245

ACE

Homo sapiens (human)

Stevioside results in decreased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP073152

ACE

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:2707

BIMP071587

ACE

Homo sapiens (human)

Dieckol results in decreased activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP071152

ACE

Rattus norvegicus (Norway rat)

APLN protein modified form inhibits the reaction [fructose results in increased expression of ACE mrna]

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP071152

ACE

Rattus norvegicus (Norway rat)

[bisphenol A co-treated with fructose] results in increased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP071152

ACE

Rattus norvegicus (Norway rat)

Fructose results in increased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP072300

ACE

Rattus norvegicus (Norway rat)

Doxorubicin affects the activity of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP072300

ACE

Rattus norvegicus (Norway rat)

Ramipril inhibits the reaction [doxorubicin results in increased expression of ACE mrna]|doxorubicin results in increased expression of ACE mRNA

https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP077135

ACE

Rattus norvegicus (Norway rat)

Resveratrol results in decreased expression of ACE protein

https://ctdbase.org/detail.go?type=gene&acc=1636