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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ACD
ACD
Homo sapiens (human)
Coumarin results in increased phosphorylation of ACD protein
https://ctdbase.org/detail.go?type=gene&acc=65057
ACD
ACD
Homo sapiens (human)
[plant extracts co-treated with resveratrol] results in decreased expression of ACD mRNA
https://ctdbase.org/detail.go?type=gene&acc=65057
ACD
ACD
Rattus norvegicus (Norway rat)
Dibutyl phthalate results in increased expression of ACD mRNA
https://ctdbase.org/detail.go?type=gene&acc=65057
ACD
ACD
Rattus norvegicus (Norway rat)
Gentamicins results in increased expression of ACD mRNA
https://ctdbase.org/detail.go?type=gene&acc=65057
acd-1
Caenorhabditis elegans
Ethanol results in increased expression of ACD-1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=182852
acdh-5
Caenorhabditis elegans
Ethanol results in decreased expression of ACDH-5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=172400
acdh-6
Caenorhabditis elegans
Ethanol results in increased expression of ACDH-6 mRNA
https://ctdbase.org/detail.go?type=gene&acc=182112
acdh-8
Caenorhabditis elegans
Ethanol results in decreased expression of ACDH-8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=173979
ACE
ACE
Danio rerio (zebrafish)
[ethanol co-treated with benzo(a)pyrene] results in decreased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [ethanol results in increased expression of ACE mrna]|ethanol results in increased expression of ACE protein|egr1 protein affects the reaction [ethanol promotes the reaction [EGR1 protein binds to ACE promoter]]|ethanol promotes the reaction [EGR1 protein binds to ACE promoter]|egr1 protein affects the reaction [ethanol results in increased expression of ACE mrna]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Ethanol results in increased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Homo sapiens (human)
Rebaudioside A results in decreased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Mus musculus (house mouse)
Formaldehyde results in increased expression of ACE protein|enalapril inhibits the reaction [formaldehyde results in increased expression of ACE protein]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Homo sapiens (human)
Boric acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Homo sapiens (human)
[toluene co-treated with ethylbenzene co-treated with xylenes] results in increased expression of ACE mrna|[toluene co-treated with ethylbenzene co-treated with xylenes] results in decreased methylation of ACE gene
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Homo sapiens (human)
[toluene co-treated with ethylbenzene co-treated with xylenes] results in increased expression of ACE mrna|[toluene co-treated with ethylbenzene co-treated with xylenes] results in decreased methylation of ACE gene
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Magnolol inhibits the reaction [monocrotaline results in increased expression of ACE protein]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Furan results in increased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Daphnia magna
Fluoranthene results in increased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Homo sapiens (human)
Nicotine results in increased expression of ACE mRNA
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Monocrotaline results in increased expression of ACE mrna|angiotensin I (1-7) inhibits the reaction [monocrotaline results in increased expression of ACE mrna]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Magnolol inhibits the reaction [monocrotaline results in increased expression of ACE protein]|monocrotaline results in increased expression of ACE protein
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Mus musculus (house mouse)
[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna|2,5-dihydroxybenzoic acid inhibits the reaction [[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna]|metformin inhibits the reaction [[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Rattus norvegicus (Norway rat)
Curcumin inhibits the reaction [paraquat affects the expression of ACE protein]
https://ctdbase.org/detail.go?type=gene&acc=1636
ACE
ACE
Danio rerio (zebrafish)
Bisphenol A results in increased methylation of ACE intron
https://ctdbase.org/detail.go?type=gene&acc=1636
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