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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ACD
|
Homo sapiens (human)
|
Coumarin results in increased phosphorylation of ACD protein
|
https://ctdbase.org/detail.go?type=gene&acc=65057
|
||
|
ACD
|
Homo sapiens (human)
|
[plant extracts co-treated with resveratrol] results in decreased expression of ACD mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=65057
|
||
|
ACD
|
Rattus norvegicus (Norway rat)
|
Dibutyl phthalate results in increased expression of ACD mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=65057
|
||
|
ACD
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ACD mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=65057
|
||
|
acd-1
|
Caenorhabditis elegans
|
Ethanol results in increased expression of ACD-1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=182852
|
||
|
acdh-5
|
Caenorhabditis elegans
|
Ethanol results in decreased expression of ACDH-5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=172400
|
||
|
acdh-6
|
Caenorhabditis elegans
|
Ethanol results in increased expression of ACDH-6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=182112
|
||
|
acdh-8
|
Caenorhabditis elegans
|
Ethanol results in decreased expression of ACDH-8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=173979
|
||
|
ACE
|
Danio rerio (zebrafish)
|
[ethanol co-treated with benzo(a)pyrene] results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [ethanol results in increased expression of ACE mrna]|ethanol results in increased expression of ACE protein|egr1 protein affects the reaction [ethanol promotes the reaction [EGR1 protein binds to ACE promoter]]|ethanol promotes the reaction [EGR1 protein binds to ACE promoter]|egr1 protein affects the reaction [ethanol results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Ethanol results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Rebaudioside A results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
Formaldehyde results in increased expression of ACE protein|enalapril inhibits the reaction [formaldehyde results in increased expression of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Boric acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
[toluene co-treated with ethylbenzene co-treated with xylenes] results in increased expression of ACE mrna|[toluene co-treated with ethylbenzene co-treated with xylenes] results in decreased methylation of ACE gene
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
[toluene co-treated with ethylbenzene co-treated with xylenes] results in increased expression of ACE mrna|[toluene co-treated with ethylbenzene co-treated with xylenes] results in decreased methylation of ACE gene
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Magnolol inhibits the reaction [monocrotaline results in increased expression of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Furan results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Daphnia magna
|
Fluoranthene results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Nicotine results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Monocrotaline results in increased expression of ACE mrna|angiotensin I (1-7) inhibits the reaction [monocrotaline results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Magnolol inhibits the reaction [monocrotaline results in increased expression of ACE protein]|monocrotaline results in increased expression of ACE protein
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna|2,5-dihydroxybenzoic acid inhibits the reaction [[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna]|metformin inhibits the reaction [[streptozocin co-treated with niacinamide] results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Curcumin inhibits the reaction [paraquat affects the expression of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Danio rerio (zebrafish)
|
Bisphenol A results in increased methylation of ACE intron
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
No matching records found on this page.