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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ACAN
|
Mus musculus (house mouse)
|
Dexamethasone results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in decreased expression of ACAN protein|dexamethasone results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Mus musculus (house mouse)
|
Oxymatrine inhibits the reaction [IL1B protein results in decreased expression of ACAN protein]
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Abrine results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol F] results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Aflatoxin B1 results in decreased methylation of ACAN gene
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Atrazine affects the methylation of ACAN gene
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased methylation of ACAN exon|benzo(a)pyrene affects the methylation of ACAN 3' utr|benzo(a)pyrene affects the methylation of ACAN promoter|benzo(a)pyrene results in increased methylation of ACAN 5' UTR
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Formaldehyde results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Mus musculus (house mouse)
|
Butylparaben results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Mus musculus (house mouse)
|
Ethanol results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Ethanol results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Melatonin results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Nicotine results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Nicotine results in decreased expression of ACAN protein
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Ethyl-p-hydroxybenzoate results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Bisphenol A results in decreased methylation of ACAN gene
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol A] results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Mus musculus (house mouse)
|
Triptonide results in increased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Rattus norvegicus (Norway rat)
|
Cocaine affects the expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
[plant extracts co-treated with resveratrol] results in decreased expression of ACAN mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
||
|
ACAN
|
Homo sapiens (human)
|
Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with ascorbic acid co-treated with dexamethasone] results in increased expression of ACAN mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=176
|
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