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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG5
Mus musculus (house mouse)
[APOE gene mutant form results in increased susceptibility to diethylhexyl phthalate] which results in decreased expression of ABCG5 protein
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
[bisphenol A co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
Diethylhexyl phthalate results in decreased expression of ABCG5 mrna|diethylhexyl phthalate results in decreased expression of ABCG5 protein
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
[ethinyl estradiol co-treated with diosgenin] results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
Diosgenin promotes the reaction [ABCG5 protein results in increased secretion of cholesterol]
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
[diosgenin results in increased expression of ABCG5 mrna] which results in increased secretion of cholesterol|diosgenin results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
Lithocholic acid results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
[lithocholic acid co-treated with pregnenolone carbonitrile] results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
Lithocholic acid results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Xenopus tropicalis (tropical clawed frog)
Dimethyl phthalate affects the expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
Rosiglitazone results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
Methyleugenol results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Danio rerio (zebrafish)
Ethanol results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
[bisphenol A co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
[hydrocarbons, chlorinated co-treated with polychlorinated biphenyls co-treated with methylmercuric chloride] results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
Estradiol results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
[bisphenol A co-treated with estradiol] results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
Estradiol affects the expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
[testosterone co-treated with estradiol] results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
Oxycodone results in increased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Mus musculus (house mouse)
Trilinolein results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Rattus norvegicus (Norway rat)
Sulfadimethoxine results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
Sulforaphane results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
Cyclosporine results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
ABCG5
Homo sapiens (human)
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCG5 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64240
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