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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG5
|
Mus musculus (house mouse)
|
Deoxycholic acid results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
SLCO1A1 protein affects the susceptibility to [deoxycholic acid results in increased expression of ABCG5 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
Cholates results in increased expression of ABCG5 protein|cholates results in increased expression of ABCG5 mrna|cholates promotes the reaction [ABCG5 protein results in increased secretion of cholesterol]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
Cholic acid results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
[NR1H4 protein mutant form inhibits the reaction [cholic acid results in increased phosphorylation of NR1H4 protein]] which results in decreased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
N-nitrosopyrrolidine results in decreased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG5 mrna]|2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG5 protein]|alisol B 23-acetate results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
Alisol B 23-acetate results in increased expression of ABCG5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG5 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Rattus norvegicus (Norway rat)
|
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCG5 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in decreased expression of ABCG5 mrna|[sodium selenite results in increased abundance of selenium] inhibits the reaction [[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in decreased expression of ABCG5 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
[vancomycin co-treated with imipenem] affects the expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
ABCG5 protein affects the export of sterols
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
ABCG5 protein affects the export of sterols
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Rattus norvegicus (Norway rat)
|
Toluene affects the expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Rattus norvegicus (Norway rat)
|
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with allethrins] results in decreased expression of ABCG5 protein
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
[bisphenol A co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
Clofibrate inhibits the reaction [PPARA gene mutant form results in increased expression of ABCG5 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
Clofibrate results in decreased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Rattus norvegicus (Norway rat)
|
Clofibrate affects the expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Rattus norvegicus (Norway rat)
|
Clofibrate results in decreased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased expression of ABCG5 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
||
|
ABCG5
|
Homo sapiens (human)
|
Benzo(a)pyrene results in decreased methylation of ABCG5 5' UTR
|
https://ctdbase.org/detail.go?type=gene&acc=64240
|
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