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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC6
|
Mus musculus (house mouse)
|
Mono-(2-ethylhexyl)phthalate results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Mus musculus (house mouse)
|
[magnesium deficiency co-treated with phosphates] promotes the reaction [ABCC6 gene mutant form results in increased susceptibility to warfarin]
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Diallyl trisulfide results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Diallyl disulfide results in decreased expression of ABCC6 mrna|diallyl disulfide results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
ABCC6 gene SNP affects the susceptibility to docetaxel
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
[docetaxel results in decreased susceptibility to docetaxel] which affects the expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
N-nitrosopyrrolidine results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:57
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCC6 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Fluorouracil results in increased expression of ABCC6 protein|abcc6 protein affects the susceptibility to fluorouracil
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Indomethacin inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Indomethacin results in decreased activity of ABCC6 protein
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
Glyphosate affects the methylation of ABCC6 gene
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Zidovudine results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Mus musculus (house mouse)
|
[diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
[diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Sus scrofa (pig)
|
Deoxynivalenol results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
Isoniazid results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
Clofibrate affects the expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Mus musculus (house mouse)
|
Dibutyl phthalate results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Rattus norvegicus (Norway rat)
|
[bisphenol A co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate] affects the methylation of ABCC6 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Valproic acid results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Mus musculus (house mouse)
|
Valproic acid affects the expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
||
|
ABCC6
|
Homo sapiens (human)
|
Butyraldehyde results in decreased expression of ABCC6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=368
|
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