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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine co-treated with choline co-treated with folic acid co-treated with betaine co-treated with vitamin B 12 co-treated with zinc co-treated with phenobarbital] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[acetaminophen co-treated with propylene glycol] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Chrysophanic acid results in increased expression of ABCC4 mrna|chrysophanic acid results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:55
|
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|
ABCC4
|
Homo sapiens (human)
|
Indican inhibits the reaction [ABCC4 protein results in increased export of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Deguelin results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Triptolide results in decreased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Triptolide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Dihydrotestosterone results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Dihydrotestosterone results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein affects the transport of glutathione analog
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased export of [2,6-dibromobenzoquinone binds to glutathione]|abcc4 protein results in increased export of [2,6-dichloro-(1,4)benzoquinone binds to glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Glutathione promotes the reaction [ABCC4 protein affects the transport of calcein AM]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein affects the export of glutathione
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Allyl sulfide results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Allyl sulfide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Uric acid inhibits the reaction [ABCC4 protein affects the transport of methotrexate]|abcc4 protein affects the export of uric acid
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[NOG protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCC4 mrna|[nog protein co-treated with phenylmercuric acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ABCC4 mrna|[nog protein co-treated with p-chloromercuribenzoic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ABCC4 mrna|[nog protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased export of cyclic gmp|daidzein inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|silymarin inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|quercetin inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|naringenin inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|resveratrol inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|hesperetin inhibits the reaction [ABCC4 protein results in increased export of cyclic GMP]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCC4 protein results in increased transport of cyclic gmp]|dipyridamole inhibits the reaction [ABCC4 protein results in increased transport of cyclic GMP]|ABCC4 protein results in increased transport of cyclic GMP
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
2-palmitoylglycerol results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Diallyl disulfide results in decreased expression of ABCC4 mrna|diallyl disulfide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Diallyl trisulfide results in decreased expression of ABCC4 mrna|diallyl trisulfide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Abrine results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
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