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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC2
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
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ABCC2
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCC2 protein|nfe2l2 protein promotes the reaction [lithocholic acid results in increased expression of ABCC2 mrna]|nfe2l2 protein promotes the reaction [lithocholic acid results in increased expression of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[lithocholic acid binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Perfluorobutyric acid results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Parathion results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Danio rerio (zebrafish)
|
Propylparaben results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Danio rerio (zebrafish)
|
Butylparaben results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Prochloraz results in increased expression of ABCC2 mrna|[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
[2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside co-treated with emodin] results in increased expression of ABCC2 protein|[2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside co-treated with emodin] results in decreased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Rosiglitazone results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Rosiglitazone results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Erucin results in increased expression of ABCC2 mrna|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mrna]|2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
1,3-butadiene results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Allyl alcohol results in increased expression of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Diquat results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ginsenoside rb2 results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Triptonide results in increased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:53
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate inhibits the reaction [ethinyl estradiol results in decreased expression of ABCC2 mrna]]|pregna-4,17-diene-3,16-dione promotes the reaction [ethinyl estradiol results in decreased expression of ABCC2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Mus musculus (house mouse)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCC2 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Homo sapiens (human)
|
Tert-butylhydroperoxide results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Go 6976 inhibits the reaction [tert-butylhydroperoxide affects the localization of ABCC2 protein]|tert-butylhydroperoxide affects the localization of ABCC2 protein|acetylcysteine inhibits the reaction [tert-butylhydroperoxide affects the localization of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Bilirubin analog inhibits the reaction [tert-butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein]|tert-butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Geraniol inhibits the reaction [fructose results in decreased expression of ABCC2 mrna]|geraniol inhibits the reaction [fructose results in decreased expression of ABCC2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
||
|
ABCC2
|
Rattus norvegicus (Norway rat)
|
Ficusin results in decreased expression of ABCC2 protein|ficusin results in decreased expression of ABCC2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1244
|
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