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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB6
|
Homo sapiens (human)
|
ABCB6 protein binds to and affects the transport of coproporphyrinogen III
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Rattus norvegicus (Norway rat)
|
Clofibrate affects the expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
AHR protein affects the reaction [benzo(a)pyrene results in increased expression of ABCB6 mrna]|benzo(a)pyrene results in increased expression of ABCB6 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Benzo(a)pyrene results in increased methylation of ABCB6 5' utr|benzo(a)pyrene results in increased methylation of ABCB6 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Mus musculus (house mouse)
|
Benzo(a)pyrene results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Zoledronic acid results in decreased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Mus musculus (house mouse)
|
1,3-butadiene results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Cannabidiol results in decreased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Chironomus riparius
|
[bisphenol A co-treated with octocrylene] results in increased expression of ABCB6 mrna|[padimate-O co-treated with bisphenol A] results in increased expression of ABCB6 mrna|[bisphenol A co-treated with padimate-O co-treated with octocrylene] results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Danio rerio (zebrafish)
|
Bisphenol A affects the expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Bisphenol A results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Bisphenol A results in increased expression of ABCB6 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Mus musculus (house mouse)
|
[ABCB6 gene mutant form results in decreased expression of CYP1A2 mrna] inhibits the reaction [CYP1A2 protein results in increased metabolism of melatonin]|[abcb6 gene mutant form results in decreased expression of CYP1A2 protein] inhibits the reaction [CYP1A2 protein results in increased metabolism of melatonin]|abcb6 gene mutant form results in decreased metabolism of melatonin
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Mus musculus (house mouse)
|
Testosterone deficiency results in decreased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Ethyl methanesulfonate results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
ABCB6 protein results in decreased susceptibility to irinotecan
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Mus musculus (house mouse)
|
Pirinixic acid results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Rattus norvegicus (Norway rat)
|
Piperonyl butoxide results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Cyclosporine results in decreased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Cyclosporine results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
||
|
ABCB6
|
Homo sapiens (human)
|
Sulforaphane results in increased expression of ABCB6 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10058
|
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