SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
HTR3A
|
Homo sapiens (human)
|
Modulator (allosteric modulator)
|
https://idrblab.net/ttd/data/target/details/T64591
|
||
|
HTR3B
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T58940
|
||
|
HTR4
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T59679
|
||
|
HTR5A
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T15571
|
||
|
HTR5A
|
Homo sapiens (human)
|
Antagonist
|
https://idrblab.net/ttd/data/target/details/T15571
|
||
|
HTR6
|
Homo sapiens (human)
|
Antagonist
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR6
|
Homo sapiens (human)
|
Antagonist
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR6
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR6
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR6
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR6
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T16691
|
||
|
HTR7
|
Homo sapiens (human)
|
Modulator (allosteric modulator)
|
https://idrblab.net/ttd/data/target/details/T79062
|
||
|
HTR7
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T79062
|
||
|
HTR7
|
Homo sapiens (human)
|
Agonist
|
https://idrblab.net/ttd/data/target/details/T79062
|
||
|
HTR7
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T79062
|
||
|
HTR7
|
Homo sapiens (human)
|
Inhibitor
|
https://idrblab.net/ttd/data/target/details/T79062
|
||
|
HTR1A
|
Homo sapiens (human)
|
Full agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1
|
||
|
HTR1A
|
Homo sapiens (human)
|
Partial agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1
|
||
|
5-HT1B
|
Drosophila melanogaster (fruit fly)
|
5-HT1B gene polymorphism affects the susceptibility to toluene
|
https://ctdbase.org/detail.go?type=gene&acc=37191
|
||
|
5-HT1B
|
Drosophila melanogaster (fruit fly)
|
5-HT1B affects the susceptibility to vitamin K 3
|
https://ctdbase.org/detail.go?type=gene&acc=37191
|
||
|
5-HT1B
|
Rattus norvegicus (Norway rat)
|
[CP 94253 binds to and results in increased activity of 5-HT1B protein] which affects the susceptibility to cocaine|n-(3-(2-dimethylamino)ethoxy-4-methoxyphenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1'-biphenyl)-4-carboxamide affects the reaction [[CP 94253 binds to and results in increased activity of 5-HT1B protein] which affects the susceptibility to cocaine]|[gr 127935 binds to and results in decreased activity of 5-HT1B protein] which results in decreased susceptibility to cocaine|[n-(3-(2-dimethylamino)ethoxy-4-methoxyphenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1'-biphenyl)-4-carboxamide binds to and results in decreased activity of 5-HT1B protein] which results in decreased susceptibility to cocaine
|
https://ctdbase.org/detail.go?type=gene&acc=37191
|
||
|
HTR1B
|
Homo sapiens (human)
|
Full agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2
|
||
|
Htr1b
|
Mus musculus (house mouse)
|
Full agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2
|
||
|
HTR1B
|
Homo sapiens (human)
|
Full agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2
|
||
|
HTR1B
|
Homo sapiens (human)
|
Full agonist
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2
|
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